Laura Prado Álvarez

Publicaciones por año

Publicaciones (9)

2001 Towards the Generation of Novel Antitumour Agents from Actinomycetes by Combinational Biosynthesis

Focus on biotechnology · J. A. Salas et al.

OA 1 cita

2001 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties

Molecular & General Genetics: MGG · Aída González et al.

OA Q1 48 citas

2001 Towards the generation of novel antitumour agents from actinomycetes by combinatorial biosynthesis

NOVEL FRONTIERS IN THE PRODUCTION OF COMPOUNDS FOR BIOMEDICAL USE, VOL 1 ·

2000 Die antitumorwirksame Hybrid-Verbindung Premithramycinon H verweist indirekt auf ein tricyclisches Intermediat der Biosynthese des Aureolsäure-Antibiotikums Mithramycin

Angewandte Chemie · Felipe Lombó et al.

5 citas

2000 The novel hybrid antitumor compound premithramycinone H provides indirect evidence for a tricyclic intermediate of the biosynthesis of the aureolic acid antibiotic mithramycin

Angewandte Chemie International Edition · Felipe Lombó et al.

Q1 29 citas

1999 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus

Molecular & General Genetics: MGG · Laura Prado et al.

58 citas

1999 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin

CHEMISTRY & BIOLOGY · Laura Prado et al.

OA 85 citas

1998 The structures of premithramycinone and demethylpremithramycinone, plausible early intermediates of the aureolic acid group antibiotic mithramycin

Chemical Communications · Jürgen Rohr et al.

OA Q1 25 citas

1996 ChemInform Abstract: Enantiospecific Synthesis of Dihydropyridines from Chiral Enamines.

ChemInform · Esther Caballero et al.

Áreas temáticas

mithramycin anticancer agents structure elucidation Streptomyces argillaceus hybrid natural products biosynthetic intermediates tricyclic intermediate genetic recombination polyketide biosynthesis type II polyketide synthase anticancer natural products enantiospecific synthesis dihydropyridines chiral enamines asymmetric synthesis pyridine synthesis actinomycetes combinatorial biosynthesis natural product discovery secondary metabolites

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Colaboración internacional

España 6

Estados Unidos 4

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